1,4-联苯基-1-丁酮合成路线 （共 73 条）
反应条件
1: 56 percent
2: 1) LDA; 2) O2; 3) SnCl2, aq. HCl; 4) aq. NaOH
View Scheme
参考文献
Freerksen, Robert W.; Selikson, Sandra J.; Wroble, Randall R.; Kyler, S. Keith; Watt, David S.
Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4087 - 4096
反应条件
1: 56 percent
2: 1) LDA; 2) O2; 3) SnCl2, aq. HCl; 4) aq. NaOH
View Scheme
参考文献
Freerksen, Robert W.; Selikson, Sandra J.; Wroble, Randall R.; Kyler, S. Keith; Watt, David S.
Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4087 - 4096
反应条件
1: I2
2: (i) O3, (ii) Zn, AcOH
View Scheme
参考文献
Kochi,J.K.
Journal of Organic Chemistry, 1963 , vol. 28, p. 1960 - 1968
反应条件
AlCl3, aluminium chloride
T=30°C;
参考文献
Husar, Branislav; Lukac, Ivan; Chmela, Stefan; Canet, Jean-Louis; Troin, Yves
Chemical Papers, 2010 , vol. 64, # 4 p. 499 - 503
反应条件
1: [IrH(1,5-cyclooctadiene)Cl(HCN(i-Pr)CHCN(C2H4PPh2))]PF6; isopropyl alcohol; potassium hydroxide / 5 h / Inert atmosphere
2: [IrH(1,5-cyclooctadiene)Cl(HCN(i-Pr)CHCN(C2H4PPh2))]PF6; potassium hydroxide / toluene / 1 h / 110 °C / Inert atmosphere
View Scheme
参考文献
Gong, Xue; Zhang, Hong; Li, Xingwei
Tetrahedron Letters, 2011 , vol. 52, # 43 p. 5596 - 5600
反应条件
phenyllithium
1.) -78 deg C, 2.) RT; Further byproducts given;
参考文献
Uno, Hidemitsu; Sakamoto, Katsuji; Semba, Fumihiko; Suzuki, Hitomi
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 1 p. 210 - 217
反应条件
1: MCPBA
2: 1.) MeLi-LiBr / 1.) -90 deg C, 1 h
3: 12 percent / PhMgBr, CuI / 1 h / -78 - 20 °C
View Scheme
参考文献
Uno, Hidemitsu; Semba, Fumihiko; Tasaka, Tadataka; Suzuki, Hitomi
Chemistry Letters, 1989 , p. 309 - 312
反应条件
1: 1.) MeLi-LiBr / 1.) ether, THF, -90 deg C, 15 min, 2.) ether THF, -90 deg C, 30 min
2: 4 percent / PhLi / 1.) -78 deg C, 2.) RT
View Scheme
参考文献
Uno, Hidemitsu; Sakamoto, Katsuji; Semba, Fumihiko; Suzuki, Hitomi
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 1 p. 210 - 217
反应条件
sulfuric acid; mercuric sulphate
参考文献
Iwai; Okajima
Yakugaku Zasshi, 1958 , vol. 78, p. 1404,1407
Chem.Abstr., 1959 , p. 8066
反应条件
chromium(VI) oxide; acetic acid
参考文献
Orechow; Tiffeneau
Bulletin de la Societe Chimique de France, 1927 , vol. <4> 41, p. 1181
