反应条件
1: 2-chloro-benzyl chloride With chloro-trimethyl-silane; ethylene dibromide; lithium chloride; zinc in tetrahydrofuran T=0 - 25°C; 2 h; Inert atmosphere; 2: chloroformic acid ethyl ester With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=-30 - 25°C; Negishi cross-coupling reaction; 6.42 h; Inert atmosphere;
参考文献
Metzger, Albrecht; Schade, Matthias A.; Knochel, Paul
Organic Letters, 2008 , vol. 10, # 6 p. 1107 - 1110