1: 1-chloro-4-bromobenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; 2: chloroformic acid ethyl ester in tetrahydrofuran; hexane T=-78°C; 3 h; 3: With ammonium chloride in tetrahydrofuran; hexane; water
1: With triethylamine in acetone T=0°C; 0.666667 h; 2: With sodium azide in water; acetone T=0°C; 1 h; 3: With tributyl-amine in diphenyl Methane; benzene T=220°C; 1.5 h;
1: With triethylamine in acetone Cooling with ice; 2: With sodium azide in water; acetone 1 h; Cooling with ice; 3: With tributyl-amine; diphenylamine T=220°C; 1.5 h;
参考文献
Asagarasu, Akira; Matsui, Teruaki; Hayashi, Hiroyuki; Tamaoki, Satoru; Yamauchi, Yukinao; Sato, Michitaka
Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 1 p. 34 - 42
