反应条件
1: 90 percent / piperidine / 24 h / Heating
2: 95 percent / Na, liq. NH3 / 2 h
3: 79 percent / triethylamine, isobutyl chloroformate / CH2Cl2 / 0.17 h / -6 °C
4: 1.) NaH / 1.) THF, -20 deg C, 1 h, 2.) THF, -20 deg C to room temperature, 1 h
5: 1.) KH, 2.) MoO5*Py*DMPU / 1.) THF, -20 deg C, 1 h, 2.) a) -20 deg C, 4 h, b) -20 deg C to room temperature
View Scheme
参考文献
Pattenden, Gerald; Shuker, Anthony J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 10 p. 1215 - 1222
