1: 1.) NH2OH*HCl, CuSO4*5H2O, conc. NH4OH / 1.) H2O, EtOH, 30 min; 2.) pyridine, reflux, overnight 2: 197 mg / (Ph3P)3RhCl / acetonitrile; H2O / 7 h / Heating View Scheme

sulfuric acid 1) 70 deg C, 1h, 2) 70 to 115 deg C, 2h, 3) 115 deg C, 15 - 30 min;

sulfuric acid

1: 1.) NH2OH*HCl, CuSO4*5H2O, conc. NH4OH / 1.) H2O, EtOH, 30 min; 2.) pyridine, reflux, overnight 2: 197 mg / (Ph3P)3RhCl / acetonitrile; H2O / 7 h / Heating 3: 25 mg / acetic anhydride / 6 h / Heating View Scheme