2: 80 percent / diethyl ether; tetrahydrofuran / 24 h / Ambient temperature 3: 80 percent / HCl, MeOH / CH2Cl2 / 0.02 h / Ambient temperature 4: 70 percent / H2O2, H2O, KF, KHCO3 / tetrahydrofuran; methanol / 0.33 h / Ambient temperature 5: 69 percent / Et3N, DMAP / CH2Cl2 / 48 h / Ambient temperature 6: 24 percent / PCl3, DMF, pyridine / tetrahydrofuran / 1 h / Ambient temperature 7: 67 percent / TBAF / tetrahydrofuran / 5 h / Ambient temperature View Scheme

diisobutylaluminium hydride in dichloromethane T=-78°C; 2 h;

2: 80 percent / diethyl ether; tetrahydrofuran / 24 h / Ambient temperature 3: 80 percent / HCl, MeOH / CH2Cl2 / 0.02 h / Ambient temperature 4: 70 percent / H2O2, H2O, KF, KHCO3 / tetrahydrofuran; methanol / 0.33 h / Ambient temperature View Scheme