4,5-二溴呋喃-2-羧酸叔丁酯合成路线 （共 3 条）
反应条件
in toluene
T=90°C; 2 h;
参考文献
DAINIPPON PHARMACEUTICAL CO., LTD.
Patent: EP1489077 A1, 2004 ;
Location in patent: Page 39 ;
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane
T=20°C; 14 h; Yield given;
参考文献
Muratake, Hideaki; Okabe, Kazuaki; Takahashi, Michiko; Tonegawa, Miyuki; Natsume, Mitsutaka
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 5 p. 799 - 806
反应条件
1: LiOH*H2O / 1,2-dimethoxy-ethane; H2O / 1 h / 20 °C
2: DMAP, EDCl*HCl / CH2Cl2 / 14 h / 20 °C
View Scheme
参考文献
Muratake, Hideaki; Okabe, Kazuaki; Takahashi, Michiko; Tonegawa, Miyuki; Natsume, Mitsutaka
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 5 p. 799 - 806
