3-氧代-3-(2-吡啶基)丙腈合成路线 (共 4 条)
反应条件
1: With sodium hydride in toluene T=65°C; 48 h; 2: With hydrogenchloride
参考文献
Tetrahedron Letters, , vol. 47, # 15 p. 2531 - 2534
反应条件
1: thionyl chloride / 0 °C / Reflux 2: sodium hydride / toluene; mineral oil / 16 h / 65 °C View Scheme
参考文献
WO2011/126903 A2, ;
WO 2011/126903 A2
反应条件
hydrazine in ethanol 24 h; Reflux;
参考文献
WO2009/111279 A1, ;
Page/Page column 111 ;
WO 2009/111279 A1
参考文献
ABBVIE INC.; Cusack, Kevin P.; Gordon, Thomas D.; Hoemann, Michael Z.; Ihle, David C.; Li, Bin; Lo Schiavo, Gloria Y.; Somal, Gagandeep K.; Friedman, Michael; Hayes, Martin E.; Bakker, Wouter Iwema
Patent: US2014/179676 A1, 2014 ;
Location in patent: Page/Page column ;