1-甲氧基-3-(三甲基硅氧基)-丁二烯合成路线 （共 70 条）
反应条件
silver trifluoromethanesulfonate in water T=20°C; aza-Diels-Alder reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 345, # 4 p. 475 - 477
反应条件
lithium methanolate; trifluoroacetic acid in N,N-dimethyl-formamide T=0°C; Diels-Alder reaction; 24 h;
参考文献
Heterocycles, , vol. 73, # C p. 255 - 261
反应条件
in benzene 6 h; Heating;
参考文献
Synthetic Communications, , vol. 21, # 21 p. 2231 - 2256
反应条件
in benzene T=25°C; 24 h;
参考文献
Jung, Michael E.; Grove, David D.
Journal of the Chemical Society, Chemical Communications, 1987 , p. 753 - 755
反应条件
zinc(II) chloride in benzene 12 h; Ambient temperature;
参考文献
Page, Philip C. Bulman; Williams, P. Howard; Collington, Eric W.; Finch, Harry
Journal of the Chemical Society, Chemical Communications, 1987 , p. 756 - 757
反应条件
in benzene
T=140°C; Diels-Alder cycloaddition reaction; 72 h; Cooling with liquid nitrogensealed;
参考文献
Della Rosa, Claudia D.; Sanchez, Juan P.; Kneeteman, Maria N.; Mancini, Pedro M.E.
Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2316 - 2319
反应条件
2,6-dimethylpyridine; ytterbium trislt;(R)-(-)-1,1'-binaphthyl-2,2'-diyl phosphategt; in dichloromethane
16 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Doyle, Michael P.; Morgan, John P.; Colyer, John T.
Journal of Organometallic Chemistry, 2005 , vol. 690, # 24-25 p. 5525 - 5532
反应条件
tetrahydrofuran; hydrogenchloride
1) benzene / 22h / reflux; Yield given. Multistep reaction;
参考文献
MERCK SHARP and DOHME CORP.; BRUBAKER, Jason; DINSMORE, Christopher J.; HOFFMAN, Dawn Marie; JUNG, Joon; LIU, Duan; PETERSON, Scott; SIU, Tony; TORRES, Luis E.; ZHANG, Hongjun; WEI, Zhongyong; SHI, Feng
Patent: WO2013/40863 A1, 2013 ;
Location in patent: Page/Page column 115 ;
WO 2013/040863 A1
反应条件
in benzene
T=150°C; 72 h;
参考文献
Paredes, Elisa; Brasca, Romina; Kneeteman, Maria; Mancini, Pedro M.E.
Tetrahedron, 2007 , vol. 63, # 18 p. 3790 - 3799
反应条件
in benzene
T=80°C; Cycloaddition; 144 h;
参考文献
Paredes; Biolatto; Kneeteman; Mancini
Tetrahedron Letters, 2000 , vol. 41, # 42 p. 8079 - 8082
