1-异氰酸-3,5-二甲氧基苯酯合成路线 （共 28 条）
反应条件
in toluene T=100°C; Cooling with ice;
参考文献
European Journal of Medicinal Chemistry, , vol. 44, # 8 p. 3318 - 3322
反应条件
in toluene 1.5 h; Heating;
参考文献
Heterocycles, , vol. 74, # C p. 731 - 742
反应条件
1: 8.7 g / sodium hydroxide (20percent) / 60 °C 5: 28.8 g / fluoroboric acid, sodium nitrite / H2O 6: 7.6 g / warming, distillation 7: 52 percent / lithium chips / 0.75 h 8: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: 8.7 g / sodium hydroxide (20percent) / 60 °C 5: 28.8 g / fluoroboric acid, sodium nitrite / H2O 6: 7.6 g / warming, distillation 7: 60 percent / lithium chips / 0.5 h 8: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: 8.7 g / sodium hydroxide (20percent) / 60 °C 5: 28.8 g / fluoroboric acid, sodium nitrite / H2O 6: 7.6 g / warming, distillation View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
sodium hydroxide T=60°C;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1658 - 1666
反应条件
1: 8.7 g / sodium hydroxide (20percent) / 60 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1658 - 1666
反应条件
1: 8.7 g / sodium hydroxide (20percent) / 60 °C 5: 28.8 g / fluoroboric acid, sodium nitrite / H2O 6: 7.6 g / warming, distillation 7: 1.) lithium / 1.) ether, 2 h 8: decarboxylation 9: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: 8.7 g / sodium hydroxide (20percent) / 60 °C 5: fluoroboric acid, sodium nitrite / H2O View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1658 - 1666
反应条件
1: 8.7 g / sodium hydroxide (20percent) / 60 °C 2: 88 percent / conc. sulphuric acid / 16 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1658 - 1666
