1: 5-methoxy-1H-indazole With trifluorormethanesulfonic acid in dichloromethane T=25 - 35°C; Inert atmosphere; 2: methyl 2,2,2-trichloroacetimidate in dichloromethane T=20°C; Inert atmosphere; regioselective reaction;

in ethyl acetate T=20°C; 5 h;

1: With N-bromosuccinmide; acetic acid in water T=20°C; 4 h; 2: With ethyl acetate in water

1: With zinc; 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0) in isobutyramide T=170°C; 6 h; 2: With water in isobutyramide