1-(氯甲基)-1H-苯并三唑合成路线 （共 26 条）
反应条件
thionyl chloride T=0°C; 1 h; Heating / reflux;
参考文献
Le Borgne, Marc; Na, Young Min; Pagniez, Fabrice; Le Baut, Guillaume; Le Pape, Patrice; Abdala, Hiam
Patent: US2004/67998 A1, 2004 ;
Location in patent: Page/Page column 23 ;
参考文献
Katritzky; Ji; Fang; Prakash
Journal of Organic Chemistry, 2001 , vol. 66, # 16 p. 5613 - 5615
反应条件
1: H2O 2: thionyl chloride View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 15 p. 2009 - 2014
反应条件
1: aq. sodium nitrite; AcOH / 2 h 2: NaH / dimethylformamide / 2 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 10 p. 2613 - 2617
反应条件
sodium hydride in N,N-dimethyl-formamide 2 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 10 p. 2613 - 2617
反应条件
sodium hydroxide 1.) EtOH, r.t., 1 h, 2.) DMF, 65-70 deg C, 15 h;
参考文献
Katritzky, Alan R.; Serdyuk, Larisa; Xie, Linghong
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 6 p. 1059 - 1064
反应条件
in methanol; toluene 2 h; Heating;
参考文献
Katritzky, Alan R.; Rachwal, Stanislaw; Rachwal, Bogumila
Journal of Organic Chemistry, 1989 , vol. 54, # 26 p. 6022 - 6029
反应条件
1: 71 percent / acetonitrile / Heating 2: 75 percent / DBU / dimethylformamide / 16 h / 115 °C View Scheme
参考文献
Katritzky; Qiu; Long; He; Steel
Journal of Organic Chemistry, 2000 , vol. 65, # 26 p. 9201 - 9205
反应条件
1: 67 percent / acetonitrile / Heating 2: 78 percent / K2CO3 / 16 h / 155 °C View Scheme
参考文献
Katritzky; Qiu; Long; He; Steel
Journal of Organic Chemistry, 2000 , vol. 65, # 26 p. 9201 - 9205
反应条件
sodium in N,N-dimethyl-formamide T=50°C; Substitution;
参考文献
Pleynet, David P.M.; Dutton, Jonathan K.; Johnson, Peter A.
Tetrahedron, 1999 , vol. 55, # 40 p. 11903 - 11926
