反应条件
1: 3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol With sodium hydride in dimethyl sulfoxide; mineral oil
0.5 h;
2: 6-chloro-nicotinic acid N-methylamide in dimethyl sulfoxide; mineral oil
T=120°C;
参考文献
Wang, Min; Gao, Mingzhang; Steele, Brandon L.; Glick-Wilson, Barbara E.; Brown-Proctor, Clive; Shekhar, Anantha; Hutchins, Gary D.; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 14 p. 4713 - 4718