1: para-chloro-benzonitrile; tri-isopropoxy-borane; lithium diisopropyl amide 2: 3-hydroxy-2,2-dimethylpropanol Title compound not separated from byproducts;
参考文献
Lysen, Morten; Hansen, Henriette M.; Begtrup, Mikael; Kristensen, Jesper L.
Journal of Organic Chemistry, 2006 , vol. 71, # 6 p. 2518 - 2520
1: With n-butyllithium in tetrahydrofuran; hexane; toluene T=-75 - -74°C; 2.25 h; 2: With hydrogenchloride; water in tetrahydrofuran; hexane; toluene T=-20 - 20°C; Product distribution / selectivity;
参考文献
ELI LILLY AND COMPANY
Patent: WO2007/87488 A2, 2007 ;
Location in patent: Page/Page column 17; 47-48 ;
1: 2-bromo-9,10-di(naphthalene-2-yl)anthracene With n-butyllithium in tetrahydrofuran T=-78°C; 1 h; 2: tri-isopropoxy-borane in tetrahydrofuran T=20°C; 3: With hydrogenchloride in tetrahydrofuran; water T=0°C;
参考文献
Samsung Mobile Display Co., Ltd.
Patent: EP2292604 A2, 2011 ;
Location in patent: Page/Page column 24-25 ;
1: 4-(3-bromophenyl)morpholine With n-butyllithium in tetrahydrofuran; hexane T=-78 - -70°C; 2 h; 2: tri-isopropoxy-borane in tetrahydrofuran; hexane T=20°C; Cooling with acetone-dry ice; 3: With water; ammonium chloride in tetrahydrofuran; hexane
参考文献
SENEXIS LIMITED; HORWELL, David Christopher; SCOPES, David Ian Carter
Patent: WO2011/144578 A1, 2011 ;
Location in patent: Page/Page column 28; 29 ;
