1: in tetrahydrofuran; toluene
T=20°C; 0.5 h; Inert atmosphere;
2: With n-hexyl lithium in tetrahydrofuran; hexane; toluene
T=-78 - -20°C;
参考文献
Magnus, Nicholas A.; Anzeveno, Peter B.; Coffey, D. Scott; Hay, David A.; Laurila, Michael E.; Schkeryantz, Jeffrey M.; Shaw, Bruce W.; Staszak, Michael A.
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 560 - 567
1: tri-isopropoxy-borane; 2-methoxy 5-cyanobenzene; lithium diisopropyl amide
2: 3-hydroxy-2,2-dimethylpropanol Title compound not separated from byproducts;
参考文献
Lysen, Morten; Hansen, Henriette M.; Begtrup, Mikael; Kristensen, Jesper L.
Journal of Organic Chemistry, 2006 , vol. 71, # 6 p. 2518 - 2520