1: ethyl acetoacetate With sodium hydride in tetrahydrofuran
T=0°C; 0.333333 h;
2: With tert.-butyl lithium in tetrahydrofuran; pentane
T=0°C; 30 h;
3: 1-iodo-butane in tetrahydrofuran; pentane
Further stages.;
参考文献
Lager, Erik; Nilsson, Jakob; stergaard Nielsen, Elsebet; Nielsen, Mogens; Liljefors, Tommy; Sterner, Olov
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 14 p. 6936 - 6948
Cook, Michael J.; Dunn, Adrian J.; Howe, Steven D.; Thomson, Andrew J.; Harrison, Kenneth J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2453 - 2458
