反应条件
1: 1.) oxygen, thiourea; 2.) pyridine, DMAP / 1.) MeOH, irradiation; 2.) CH2Cl2 2: 1.) 1 molpercent OsO4; 2.) TsOH / 1.) THF, acetone; 3: 1.) KOH; 2.)dicyclohexylcarbodiimide, Me2SO, trifluoroacetic acid, pyridine / 1.) MeOH; 2.) benzene 5: 1.) copper(I) iodide, tributylphosphine; 2.) HMPA / 1.) THF, -78 deg C; 2.) -30 deg C, 3 h 6: 89 percent / aqu. HF, pyridine / acetonitrile 7: 98 percent / Al(Hg) / tetrahydrofuran; H2O 8: enzyme View Scheme
参考文献
Johnson, Carl R.; Penning, Thomas D.
Journal of the American Chemical Society, 1986 , vol. 108, # 18 p. 5655 - 5656
