5-乙酰基苯并[d]噁唑-2(3H)-酮合成路线 （共 14 条）
反应条件
triethylamine in tetrahydrofuran
T=0 - 20°C; 1 h;
参考文献
Bovy, Philippe R.; Cecchi, Roberto; Courtemanche, Gilles; Croci, Tiziano; Oliva, Ambrogio; Viviani, Nunzia
Patent: US2004/53916 A1, 2004 ;
Location in patent: Page/Page column 7 ;
US 20040053916 A1
反应条件
1: 1-lt;3-(acetylamino)-4-hydroxyphenylgt;ethanone 0.75 h; Heating / refluxAcidic conditions;
2: urea With hydrogenchloride in water
T=140 - 170°C; 4 h;
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: EP1785426 A1, 2007 ;
Location in patent: Page/Page column 42 ;
反应条件
[bis(acetoxy)iodo]benzene; potassium hydroxide in methanol
T=0°C; Hofmann Rearrangement; 1.08333 h;
参考文献
Ivanova, Yordanka B.; Momekov, Georgi T.; Petrov, Ognyan I.
Heterocyclic Communications, 2013 , vol. 19, # 1 p. 23 - 28
反应条件
sodium azide; iodine; sodium hydrogencarbonate in N,N-dimethyl-formamide
T=100°C; 2 h;
参考文献
Rajendar; Kant, Ruchir; Narender
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 18 p. 3591 - 3596
反应条件
in benzene
0.333333 h; Irradiation; Further byproducts given;
参考文献
Sigman, Michael E.; Autrey, Tom; Schuster, Gary B.
Journal of the American Chemical Society, 1988 , vol. 110, # 13 p. 4297 - 4305
反应条件
hydrogenchloride
a) 140 deg C, 1.5 h, b) 170 deg C, 2.5 h;
参考文献
Aichaoui, Hocine; Poupaert, Jacques H.; Lesieur, Daniel; Henichart, Jean-Pierre
Tetrahedron, 1991 , vol. 47, # 33 p. 6649 - 6654
反应条件
hexafluorobenzene
1.5 h; Irradiation;
参考文献
Sigman, Michael E.; Autrey, Tom; Schuster, Gary B.
Journal of the American Chemical Society, 1988 , vol. 110, # 13 p. 4297 - 4305
反应条件
1: 1.) NaH; 2.) NaN3 / 1.) THF, 12 h, room temp.; 2.) THF, 12 h, room temp.
2: hexafluorobenzene / 1.5 h / Irradiation
View Scheme
参考文献
Sigman, Michael E.; Autrey, Tom; Schuster, Gary B.
Journal of the American Chemical Society, 1988 , vol. 110, # 13 p. 4297 - 4305
反应条件
in benzene
0.333333 h; Irradiation;
参考文献
Sigman, Michael E.; Autrey, Tom; Schuster, Gary B.
Journal of the American Chemical Society, 1988 , vol. 110, # 13 p. 4297 - 4305
反应条件
1: C3H7NO*AlCl3
2: hydrogenchloride / water
3: tetrahydrofuran
View Scheme
参考文献
Ivanova, Yordanka B.; Momekov, Georgi T.; Petrov, Ognyan I.
Heterocyclic Communications, 2013 , vol. 19, # 1 p. 23 - 28
