1-(1,3-苯并噻唑-2-基)-2-溴-1-乙酮合成路线 （共 13 条）
反应条件
1: cyclobenzothiazole With n-butyllithium in hexanes; diethyl ether T=-78°C; 0.25 h; 2: bromoacetic acid methyl ester in hexanes; diethyl ether T=-78°C; 0.25 h;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/4117 A1, 2008 ;
Location in patent: Page/Page column 143 ;
反应条件
copper(ll) bromide in ethyl acetate 24 h; Heating;
参考文献
Podea, Paula Veronica; Paizs, Csaba; Tosa, Monica Ioana; Irimie, Florin Dan
Tetrahedron Asymmetry, 2008 , vol. 19, # 16 p. 1959 - 1964
反应条件
in dichloromethane 3 h;
参考文献
WO2004/106345 A2, ;
Page 50 ;
反应条件
1: K2Cr2O7 / acetic acid / 1 h / Heating 2: Br2 / CHCl3 View Scheme
参考文献
Indian Journal of Chemistry, , vol. 8, p. 882 - 884
反应条件
1: xylene / 8 h / Heating 2: K2Cr2O7 / acetic acid / 1 h / Heating 3: Br2 / CHCl3 View Scheme
参考文献
Indian Journal of Chemistry, , vol. 8, p. 882 - 884
反应条件
in diethyl ether; benzene
Heating;
参考文献
Sawhney,S.N.; Singh,J.
Indian Journal of Chemistry, 1970 , vol. 8, p. 882 - 884
反应条件
1: ethanol / 1 h / Heating
2: aq. NaOH
View Scheme
参考文献
Singh,S.P. et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1978 , vol. 16B, p. 334 - 336
反应条件
1: ethanol / 1 h / Heating
2: aq. NaOH / ethanol / 1 h / Heating
View Scheme
参考文献
Singh,S.P. et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1978 , vol. 16B, p. 334 - 336
反应条件
1: ethanol / 1 h / Heating
2: aq. NaOH / ethanol / Heating
View Scheme
参考文献
Singh,S.P. et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1978 , vol. 16B, p. 334 - 336
反应条件
1: ethanol / 1 h / Heating
2: aq. NaOH / ethanol / Heating
View Scheme
参考文献
Singh,S.P. et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1978 , vol. 16B, p. 334 - 336
