4-甲基-1,3-噻唑-5-羰酰氯合成路线 (共 4 条)
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide in toluene
参考文献
Mitsui Toatsu Chemicals, Inc.
Patent: US5136042 A1, 1992 ;
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
参考文献
WO2009/15208 A1, ;
Page/Page column 86 ;
WO 2009/015208 A1
反应条件
hydrogen; Pd-BaSO4 in xylene T=140°C;
参考文献
Bai, Nan; Sha, Yaowu; Meng, Ge
Molecules, 2008 , vol. 13, # 4 p. 943 - 947
参考文献
GILEAD CONNECTICUT, INC.; GENENTECH, INC.; CURRIE, Kevin S.; WANG, Xiaojing; YOUNG, Wendy, B.
Patent: WO2012/30990 A1, 2012 ;
Location in patent: Page/Page column 79-80 ;
WO 2012/030990 A1