2-氯-4,5-二氢-1H-咪唑合成路线 （共 12 条）
反应条件
in methanol; N,N-dimethyl-formamide
参考文献
Kan, Wai Ming; Lin, Shih-Hsun; Chern, Ching-Yuh
Synthetic Communications, 2005 , vol. 35, # 20 p. 2633 - 2639
反应条件
phosphorus pentachloride in acetonitrile
T=20°C; 72 h;
参考文献
Gomez-SanJuan, Asier; Botija, Jose Manuel; Mendez, Almudena; Sotomayor, Nuria; Letea, Esther
Arkivoc, 2014 , vol. 2014, # 2 p. 44 - 56
反应条件
chlorine in water
T=45°C; 2.5 h;
参考文献
HOPITAL SAINTE-JUSTINE
Patent: WO2005/12247 A1, 2005 ;
Location in patent: Page/Page column 29 ;
反应条件
triethylamine in N,N-dimethyl-formamide
T=35°C; 0.0666667 h;
参考文献
Etemad-Moghadam, G.; Blonski, C.; Gasc, M. B.; Perie, J. J.; Klaebe, A.
Phosphorus and Sulfur and the Related Elements, 1983 , vol. 14, p. 367 - 376
反应条件
in dichloromethane
T=20 - 22°C; 12 h;
参考文献
Kornicka, Anita; Hudson, Alan L.; Bednarski, Patrick J.
Acta Poloniae Pharmaceutica - Drug Research, 2009 , vol. 66, # 5 p. 523 - 534
反应条件
potassium carbonate
T=5°C;
参考文献
Saczewski, Franciszek; Foks, Henryk
Synthesis, 1981 , # 2 p. 154 - 155
反应条件
in dichloromethane
T=20°C; 12 h;
参考文献
Kornicka; Saczewski; Petrusewicz; Rejdych; Tyacke; Hudson; Nutt
Polish Journal of Chemistry, 2005 , vol. 79, # 1 p. 89 - 100
反应条件
1: in dichloromethane
T=20°C; 17 h;
2: With sodium hydroxide in water
0.5 h;
参考文献
Kornicka, Anita; Saczewski, Franciszek; Gdaniec, Maria
Molecules, 2004 , vol. 9, # 3 p. 86 - 101
反应条件
in dichloromethane
T=20°C; 12 h;
参考文献
Kornicka, Anita; Gdaniec, Maria
Heterocycles, 2007 , vol. 71, # 9 p. 1907 - 1917
