(E)-3-(1H-咪唑-4-基)丙烯酸甲酯单盐酸盐合成路线 （共 6 条）
反应条件
1: 75 percent / triethylamine / tetrahydrofuran / 16 h / 20 °C 2: 99 percent / H2 / Pd/C / methanol / 4 h 3: 70 percent / LiAlH4 / tetrahydrofuran / 6 h / Heating View Scheme
参考文献
Kitbunnadaj, Ruengwit; Hoffmann, Marcel; Fratantoni, Silvina A.; Bongers, Gerold; Bakker, Remko A.; Wieland, Kerstin; El Jilali, Ahmed; De Esch, Iwan J. P.; Menge, Wiro M. P. B.; Timmerman, Henk; Leurs, Rob
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 23 p. 6309 - 6323
反应条件
hydrogen; triethylamine; palladium on activated charcoal in methanol T=20°C; 24 h; atmospheric pressure;
参考文献
Gupta, Preeti; Hameed, Shahul; Jain, Rahul
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 9 p. 805 - 814
反应条件
1: 75 percent / triethylamine / tetrahydrofuran / 16 h / 20 °C 2: 99 percent / H2 / Pd/C / methanol / 4 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 13, # 23 p. 6309 - 6323
反应条件
hydrogenchloride
T=20°C;
参考文献
Gupta, Preeti; Hameed, Shahul; Jain, Rahul
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 9 p. 805 - 814
参考文献
Merck and Co., Inc.
Patent: US5932606 A1, 1999 ;
US 5932606 A
反应条件
NaH in N,N-dimethyl-formamide
参考文献
Merck and Co., Inc.
Patent: US5648368 A1, 1997 ;
