3-乙酰基-4-羟基-1-甲基-2(1H)-喹啉酮合成路线 （共 6 条）
反应条件
hydrogenchloride; zinc in ethanol; acetic acid 0.0833333 h; Heating;
参考文献
Kappe, Thomas; Aigner, Rudolf; Roschger, Peter; Schnell, Barbara; Stadlbauer, Wolfgang
Tetrahedron, 1995 , vol. 51, # 47 p. 12923 - 12928
反应条件
sulfuric acid T=140°C; 0.25 h;
参考文献
Razzaq, Tahseen; Kappe, C. Oliver
Tetrahedron Letters, 2007 , vol. 48, # 14 p. 2513 - 2517
反应条件
sodium hydroxide in water; ethylene glycol
1 h; Heating;
参考文献
Razzaq, Tahseen; Kappe, C. Oliver
Tetrahedron Letters, 2007 , vol. 48, # 14 p. 2513 - 2517
反应条件
sodium hydride in tetrahydrofuran
Methylation; 1 h; Heating;
参考文献
Mitsos, Christos; Petrou, John; Igglessi-Markopoulou, Olga; Markopoulos, John
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 4 p. 881 - 887
反应条件
potassium hydroxide
Heating;
参考文献
Kappe, Thomas; Aigner, Rudolf; Hohengassner, Peter; Stadlbauer, Wolfgang
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1994 , vol. 336, # 7 p. 596 - 601
反应条件
1: 81 percent / diphenyl ether / 1.37 h / microwave irradiation
2: 93 percent / sodium hydroxyde / ethanol; H2O / 0.02 h / 190 °C / microwave irradiation
View Scheme
参考文献
Razzaq, Tahseen; Kappe, C. Oliver
Tetrahedron Letters, 2007 , vol. 48, # 14 p. 2513 - 2517
