1: 4.6 g / pyridine 2: 1. BF3*Et2O 2. trimethylsilyl trifluoromethanesulfonate / 1. CH2Cl2, room temperature 2. 1,2-dichloroethane 3: NaOCH3 / methanol View Scheme

1: chloroform; water; sodium acetate 2: chloroform; titanium (IV)-chloride View Scheme

1: 4.6 g / pyridine 2: 1. BF3*Et2O 2. trimethylsilyl trifluoromethanesulfonate / 1. CH2Cl2, room temperature 2. 1,2-dichloroethane 3: NaOCH3 / methanol 4: 3 g / p-TosOH / acetone / 1 h / Heating 5: barium hydroxide, barium oxide / dimethylformamide 6: 1.89 g / amberlyst 15 (H+) / methanol; H2O / 6 h / Ambient temperature View Scheme

1: 4.6 g / pyridine 2: 1. BF3*Et2O 2. trimethylsilyl trifluoromethanesulfonate / 1. CH2Cl2, room temperature 2. 1,2-dichloroethane 3: NaOCH3 / methanol 4: 3 g / p-TosOH / acetone / 1 h / Heating View Scheme

1: 4.6 g / pyridine 2: 1. BF3*Et2O 2. trimethylsilyl trifluoromethanesulfonate / 1. CH2Cl2, room temperature 2. 1,2-dichloroethane 3: NaOCH3 / methanol 4: 3 g / p-TosOH / acetone / 1 h / Heating 5: barium hydroxide, barium oxide / dimethylformamide 6: 1.89 g / amberlyst 15 (H+) / methanol; H2O / 6 h / Ambient temperature 7: 69 percent / dibutyltin oxide, tetrabutylammonium iodide / benzene / 24 h / Heating View Scheme

sodium hydrogencarbonate; acetone

4-(N,N-dimethlyamino)pyridine in dichloromethane 2 h;

triethylamine in dichloromethane T=0°C; 0.5 h;

triethylamine in dichloromethane

triethylamine 1.) pyridine, 75 min, 2.) 90-95 deg C, 10 min; Yield given. Multistep reaction;