N,N-二乙基-2-氯丙酰胺合成路线 （共 4 条）
反应条件
aluminium trichloride in toluene
参考文献
Stauffer Chemical Company
Patent: US4358612 A1, 1982 ;
反应条件
triethylamine in ethyl acetate 2 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 3 p. 727 - 734
参考文献
Larizza; Pellegrino
Gazzetta Chimica Italiana, 1959 , vol. 89, p. 2018,2020
反应条件
1.1: lithium diisopropylamide / tetrahydrofuran / 0.17 h / -78 °C
1.2: 90 percent / tetrahydrofuran / -78 - 25 °C
2.1: 95 percent / SmI2 / tetrahydrofuran / 0.5 h / 25 °C
View Scheme
参考文献
Concellon, Jose M.; Perez-Andres, Juan A.; Rodriguez-Solla, Humberto
Chemistry - A European Journal, 2001 , vol. 7, # 14 p. 3062 - 3068
