反应条件
1.1: t-BuLi / tetrahydrofuran; diethyl ether / 0.08 h / -78 °C
1.2: CuBr*SMe2 / diethyl ether; various solvent(s) / 12 h / -40 - 20 °C
1.3: H2O
2.1: 82 percent / p-TsOH / CH2Cl2 / 2 h / 20 °C
3.1: 90 percent / Bu4NF / tetrahydrofuran / 12 h / 20 °C
4.1: NaH; 15-crown-5 / tetrahydrofuran / 14 h / Heating
4.2: 93 percent / Bu4NF / tetrahydrofuran
5.1: 59 percent / (PhO)2P(O)N3; DIAD; PPh3 / toluene / 12 h / 20 °C
6.1: 82 percent / p-TsOH / methanol / 12 h / 20 °C
7.1: Zn; NH4Cl / methanol / 12 h / 20 °C
View Scheme
参考文献
Milne, Jacqueline E; Jarowicki, Krzysztof; Kocienski, Philip J; Alonso, Jorge
Chemical communications (Cambridge, England), 2002 , # 5 p. 426 - 427
