1-(3-乙基-2,6-二羟基苯基)-1-乙酮合成路线 （共 15 条）
反应条件
hydrogenchloride; amalgamated zinc
参考文献
Rosenmund; Buchwald; Deligiannis
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 342,348
反应条件
Bei 10-stdg. Erhitzen;
参考文献
Rosenmund; Buchwald; Deligiannis
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 342,348
反应条件
sodium hydroxide
Hydrolysis; 3 h; Heating;
参考文献
Tsujihara, Kenji; Hongu, Mitsuya; Saito, Kunio; Kawanishi, Hiroyuki; Kuriyama, Kayoko; Matsumoto, Mamoru; Akira, Oku; Ueta, Kiichiro; Tsuda, Minoru; Saito, Akira
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5311 - 5324
参考文献
MITSUI PETROCHEMICAL INDUSTRIES, LTD.
Patent: EP331422 A3, 1991 ;
反应条件
1: 94 percent / 3 h / Heating
2: 76 percent / AlCl3 / 1 h / 170 °C
3: 81 percent / aq. NaOH / 3 h / Heating
View Scheme
参考文献
Tsujihara, Kenji; Hongu, Mitsuya; Saito, Kunio; Kawanishi, Hiroyuki; Kuriyama, Kayoko; Matsumoto, Mamoru; Akira, Oku; Ueta, Kiichiro; Tsuda, Minoru; Saito, Akira
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5311 - 5324
反应条件
1: 76 percent / AlCl3 / 1 h / 170 °C
2: 81 percent / aq. NaOH / 3 h / Heating
View Scheme
参考文献
Tsujihara, Kenji; Hongu, Mitsuya; Saito, Kunio; Kawanishi, Hiroyuki; Kuriyama, Kayoko; Matsumoto, Mamoru; Akira, Oku; Ueta, Kiichiro; Tsuda, Minoru; Saito, Akira
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5311 - 5324
反应条件
1: 90 percent / H2SO4 / 14 h / 20 °C
2: 94 percent / 3 h / Heating
3: 76 percent / AlCl3 / 1 h / 170 °C
4: 81 percent / aq. NaOH / 3 h / Heating
View Scheme
参考文献
Tsujihara, Kenji; Hongu, Mitsuya; Saito, Kunio; Kawanishi, Hiroyuki; Kuriyama, Kayoko; Matsumoto, Mamoru; Akira, Oku; Ueta, Kiichiro; Tsuda, Minoru; Saito, Akira
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5311 - 5324
反应条件
1: sodium acetate
2: AlCl3
3: aqueous HCl
View Scheme
参考文献
Setalvad et al.
Journal of the Indian Chemical Society, 1952 , vol. 29, p. 915,917, 919
反应条件
palladium; acetic acid
Hydrogenation;
参考文献
Rosenmund; Buchwald; Deligiannis
Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 342,348
参考文献
Setalvad et al.
Journal of the Indian Chemical Society, 1952 , vol. 29, p. 915,917, 919
