1: hexan-1-ol With n-butyllithium in tetrahydrofuran; hexane T=20°C; Metallation; 0.25 h; 2: 2,2-dimethyl-propionic acid 1-(2,5-dichloro-phenyl)-2,2-bis-methylsulfanyl-vinyl ester in tetrahydrofuran; hexane Acylation; 1 h; Heating;

1.1: NaH / tetrahydrofuran 1.2: 89 percent / tetrahydrofuran / 0.5 h / 20 °C 2.1: BuLi / hexane; tetrahydrofuran / 0.25 h / 20 °C 2.2: 87 percent / hexane; tetrahydrofuran / 1 h / Heating View Scheme

in toluene T=80°C; 18 h;

in toluene T=80°C; Acylation; 18 h;

phosphoric acid