4,4-二甲氧基-2-丁酮合成路线 （共 125 条）
反应条件
titanium tetrachloride
参考文献
Ojima,I.; Kumagai,M.
Chemistry Letters, 1978 , p. 575 - 578
反应条件
water; bromine; barium carbonate
unter Belichtung;
参考文献
Ichihara,A. et al.
Bulletin of the Chemical Society of Japan, 1965 , vol. 38, p. 1158 - 1161
反应条件
sodium acetate; acetic acid; zinc in water
T=78°C; 2 h; Yield given;
参考文献
Smith, Kevin M.; Fujinari, Eugene M.; Pandey, Ravindra K.; Tabba, Hani D.
Journal of Organic Chemistry, 1986 , vol. 51, # 24 p. 4667 - 4676
反应条件
acetic acid; zinc in water
T=100°C; 1 h; Yield given;
参考文献
Clezy, Peter S.; Phuc, Le van; Prashar, Jognandan K.
Australian Journal of Chemistry, 1991 , vol. 44, # 8 p. 1061 - 1075
反应条件
hydrogenchloride
0.333333 h;
参考文献
Teuber; Schumann; Reinehr; Gholami
1983 , vol. NO. 10, p. 1744 - 1759
参考文献
Teuber; Schumann; Reinehr; Gholami
1983 , vol. NO. 10, p. 1744 - 1759
反应条件
hydrogenchloride
2 h;
参考文献
Teuber; Schumann; Reinehr; Gholami
1983 , vol. NO. 10, p. 1744 - 1759
反应条件
hydrogenchloride
0.5 h;
参考文献
Teuber; Schumann; Reinehr; Gholami
1983 , vol. NO. 10, p. 1744 - 1759
反应条件
1: With hydrogenchloride in water
T=20°C; 0.5 h;
2: With sodium nitrite in water
T=0°C; 0.5 h;
3: With hydrazine hydrate; acetic acid in water
T=20°C; 0.166667 h;
参考文献
Semichenko; Frolenko; Root; Suboch
Russian Journal of Organic Chemistry, 2011 , vol. 47, # 4 p. 622 - 623
反应条件
1: With sodium methylate in methanol; ethanol
T=50 - 55°C; Industry scale;
2: With water; sodium hydroxide in methanol; ethanol
1 h; Industry scale;
3: With hydrogenchloride in methanol; ethanol; water
pH=2; Industry scale; Product distribution / selectivity;
参考文献
AstraZeneca AB
Patent: US2011/82155 A1, 2011 ;
Location in patent: Page/Page column 23 ;
US 20110082155 A1
