4,4-二甲氧基-2-丁酮合成路线 （共 125 条）
反应条件
methanol; sodium methylate
参考文献
Burness
Journal of Organic Chemistry, 1956 , vol. 21, p. 102
Org. Synth. Coll. Vol., 1963 , vol. IV, p. 628
参考文献
Degussa AG
Patent: EP1457489 A1, 2004 ;
Location in patent: Page 3 ;
反应条件
diethyl ether; sodium methylate Erhitzen des erhaltenen 2,3-Epoxy-5,5-dimethoxy-3-methyl-valeriansaeure-methylesters unter Abdestillieren von Methanol auf 160grad;
参考文献
Mal, Dipakranjan; Bandhyopadhyay, Mousumi; Datta; Murty, Kadiyala V. S. N.
Tetrahedron, 1998 , vol. 54, # 26 p. 7525 - 7538
反应条件
hydrogenchloride in ethanol 1 h;
参考文献
Lee, Thomas W. S.; Rettig, Steven J.; Stewart, Ross; Trotter, James
Canadian Journal of Chemistry, 1984 , vol. 62, p. 1194 - 1202
参考文献
Yamada
Yakugaku Zasshi, 1951 , vol. 71, p. 1349,1354
Chem.Abstr., 1952 , p. 8033
反应条件
hydrogenchloride in water T=60°C; 0.25 h;
参考文献
Arora, Nidhi; Chen, Shaoqing; Hermann, Johannes Cornelius; Kuglstatter, Adreas; Labadie, Sharada Shenvi; Lin, Clara Jeou Jen; Lucas, Matthew C.; Moore, Amy Geraldine; Papp, Eva; Talamas, Francisco Xavier; Wanner, Jutta; Zhai, Yansheng
Patent: US2012/15962 A1, 2012 ;
Location in patent: Page/Page column 68 ;
US 20120015962 A1
反应条件
n-butyllithium 1.) THF, hexane, 0 deg C, 30 min, 2.) THF, hexane, RT, overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ono, Machiko; Yoshida, Norio; Kokubu, Yuki; Sato, Eiji; Akita, Hiroyuki
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 9 p. 1428 - 1434
参考文献
Allen et al.
Journal of Organic Chemistry, 1959 , vol. 24, p. 787,792
参考文献
Burness
Journal of Organic Chemistry, 1956 , vol. 21, p. 102
Org. Synth. Coll. Vol., 1963 , vol. IV, p. 628
反应条件
methanol; sodium methylate
参考文献
Burness
Journal of Organic Chemistry, 1956 , vol. 21, p. 102
Org. Synth. Coll. Vol., 1963 , vol. IV, p. 628
