5-氯-1-苯基-1H-吡唑-4-羧酸合成路线 (共 3 条)
反应条件
1: With lithium hydroxide in tetrahydrofuran; methanol; water
T=70°C; 1 h;
2: With hydrogenchloride in tetrahydrofuran; methanol; water
pH=3;
参考文献
Gillespie, Paul; Guertin, Kevin Richard; Qi, Lida; Zhang, Qiang
Patent: US2009/23709 A1, 2009 ;
Location in patent: Page/Page column 12 ;
US 20090023709 A1
反应条件
potassium permanganate in water; tert-butyl alcohol
T=70 - 80°C; 3 h;
参考文献
Datterl, Barbara; Troestner, Nicole; Kucharski, Dorota; Holzer, Wolfgang
Molecules, 2010 , vol. 15, # 9 p. 6106 - 6126
反应条件
sulfuric acid
8 h; Reflux;
参考文献
Datterl, Barbara; Troestner, Nicole; Kucharski, Dorota; Holzer, Wolfgang
Molecules, 2010 , vol. 15, # 9 p. 6106 - 6126