3-甲基-2-硝基苯甲酸合成路线 （共 57 条）
反应条件
1.1: 99 percent / H2 / Pd/C / ethanol / 20 °C / 760 Torr 2.1: H2SO4 / H2O / 1 h / 20 °C 2.2: NaNO2 / H2O / 1.5 h / 10 °C 2.3: 84 percent / KI; Cu powder / H2O / 30 °C View Scheme
参考文献
Moorthy, Jarugu Narasimha; Senapati, Kalyan; Parida, Keshaba Nanda; Jhulki, Samik; Sooraj, Kunnikuruvan; Nair, Nisanth N.
Journal of Organic Chemistry, 2011 , vol. 76, # 23 p. 9593 - 9601
反应条件
1.1: 99 percent / H2 / Pd/C / ethanol / 20 °C / 760 Torr 2.1: H2SO4 / H2O / 1 h / 20 °C 2.2: NaNO2 / H2O / 1.5 h / 10 °C 2.3: 84 percent / KI; Cu powder / H2O / 30 °C 3.1: 90 percent / SOCl2 / 3 h / Heating 4.1: 93 percent / Cu / dimethylformamide / 5.5 h / Heating 5.1: 100 percent / LiAlH4 / diethyl ether / 5 h / Heating View Scheme
参考文献
Keller, Felix; Rippert, Andreas Johannes
Helvetica Chimica Acta, 1999 , vol. 82, # 1 p. 125 - 137
反应条件
1: 74 percent / dimethylformamide / 24 h / 130 - 140 °C 2: 80 percent / iron powder, acetic acid / ethanol / 80 °C View Scheme
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 22, # 1 p. 36 - 37
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 22, # 1 p. 44 - 45
反应条件
1: tin; hydrochloric acid 2: 130 °C View Scheme
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
1: 99 percent / H2 / Pd/C / ethanol / 20 °C / 25857.4 Torr 2: 88 percent / HBr; DMSO / 16 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 16 p. 5921 - 5929
反应条件
potassium permanganate
参考文献
Noelting; Gachot
Chemische Berichte, 1906 , vol. 39, p. 73
反应条件
1: zinc dust; alkaline alcohol 2: hydrogen chloride View Scheme
参考文献
Bulletin de la Societe Chimique de France, , vol. <4> 1, p. 216
Bulletin de la Societe Chimique de France, , vol. <4> 9, p. 602,657
反应条件
1: 99 percent / H2 / Pd/C / ethanol / 20 °C / 25857.4 Torr
2: 87 percent / 2 h / Heating
View Scheme
参考文献
Montoya-Pelaez, Pedro J.; Uh, Yoon-Seo; Lata, Christopher; Thompson, Matthew P.; Lemieux, Robert P.; Crudden, Cathleen M.
Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 5921 - 5929
反应条件
1: H2 / Pd/C
2: 78 percent / NaNO2, Cu(I)-salt
3: 95 percent / LiAlH4 / diethyl ether
4: 93 percent / PBr3 / toluene
View Scheme
参考文献
Keller, Felix; Rippert, Andreas Johannes
Helvetica Chimica Acta, 1999 , vol. 82, # 1 p. 125 - 137
反应条件
in N,N-dimethyl-formamide
T=130 - 140°C; 24 h;
参考文献
Dulenko, V. I.; Nikolyukin, Yu. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1986 , vol. 22, # 1 p. 36 - 37
Khimiya Geterotsiklicheskikh Soedinenii, 1986 , vol. 22, # 1 p. 44 - 45
