5-三氟甲基-1H-吡唑-4-羧酸合成路线 （共 2 条）
反应条件
sodium hydroxide in ethanol; water 72 h; Heating / reflux;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/54974 A2, 2004 ;
Location in patent: Page 452 ;
WO 2004/054974 A2
反应条件
1: hydrazine hydrate / ethanol / 12 h / 20 °C / Inert atmosphere 2: hydrogenchloride; acetic acid / water / 6 h / Inert atmosphere; Reflux View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 1 p. 47 - 56
