(Z)-4-辛烯-1-醇合成路线 （共 11 条）
反应条件
1: 90 percent / triphenylphosphine, bromine / CCl4 / 1) 15 deg C, 1 h; 2) room temp., 15 h. 2: 1) cuprous iodide, 2,2'-bipyridyl 2) Mg / 1) abs. THF, 20 deg C, 0.5 h; 2) abs. THF, 2 h at 2 deg C and 15 h at room temp. 3: 1) p-toluenesulfonic acid, water; 2) pyridine / 1) MeOH, room temp., 15 h; 2) room temp., 24 h. View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
diisobutylaluminium hydride in diethyl ether; toluene
T=-10°C; 2 h;
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
hydrogen; Lindlar's catalyst; Pb-poisoned Pd
参考文献
Vasil'ev, A. A.; Cherkaev, G. V.; Nikitina, M. A.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 5.1 p. 735 - 739
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 5 p. 889 - 894
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Bestmann; Koschatzky; Schaetzke; et al.
1981 , vol. No. 9, p. 1705 - 1720
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II) in benzene
T=70°C; 20 h;
参考文献
Wenkert, Ernest; Ferreira, Vitor F.; Michelotti, Enrique L.; Tingoli, Marco
Journal of Organic Chemistry, 1985 , vol. 50, # 5 p. 719 - 721
反应条件
1: 70 percent / NaI / acetone / 20 h / Heating
2: 1.) CH3COOK, dibenzo-18-crown-6, 2.) aq. KOH / 1.) CH3CN, reflux, 30 h, 2.) MeOH, 30 min
3: 88 percent / H2 / Pd,Pb/CaCO3
View Scheme
参考文献
Vasil'ev, A. A.; Cherkaev, G. V.; Nikitina, M. A.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 5.1 p. 735 - 739
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 5 p. 889 - 894
反应条件
1: 85 percent / NaI, zinc dust / bis-(2-methoxy-ethyl) ether / 1.5 h / 65 - 70 °C
2: 95 percent / 5percent aq. HCl / acetone / 6 h / Ambient temperature
3: 95 percent / diisobutylaluminum hydride / diethyl ether; toluene / 2 h / -10 °C
View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 95 percent / 5percent aq. HCl / acetone / 6 h / Ambient temperature
2: 95 percent / diisobutylaluminum hydride / diethyl ether; toluene / 2 h / -10 °C
View Scheme
参考文献
Odinokov, V. N.; Ishmuratov, G. Yu.; Galeeva, R. I.; Kharisov, R. Ya.; Sokol'skaya, O. V.; at al.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 4 p. 646 - 651
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 4 p. 719 - 724
反应条件
1: 1.) CH3COOK, dibenzo-18-crown-6, 2.) aq. KOH / 1.) CH3CN, reflux, 30 h, 2.) MeOH, 30 min
2: 88 percent / H2 / Pd,Pb/CaCO3
View Scheme
参考文献
Vasil'ev, A. A.; Cherkaev, G. V.; Nikitina, M. A.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 5.1 p. 735 - 739
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 5 p. 889 - 894
反应条件
(i) KOtBu, nBuLi, hexane, (ii) /BRN= 102378/, Et2O; Multistep reaction;
参考文献
Schlosser,M. et al.
Helvetica Chimica Acta, 1974 , vol. 57, p. 1567 - 1576
