1: 4-bromo-2,6-dimethylbenzenamine With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 0.5 h; Sonication; 2: copper (I) cyanide With potassium cyanide in water T=70°C; 0.5 h;
1: 4-bromo-2,6-dimethylbenzenamine With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 0.5 h; Sonication; 2: copper (I) cyanide; potassium cyanide With sodium hydrogencarbonate in water T=70°C; Sandmeyer Reaction; 0.5 h;
参考文献
Ferring B.V.
Patent: EP1449844 A1, 2004 ;
Location in patent: Page 23 ;
EP 1449844 A1
