5,6-二氨基-1,3-二甲基尿苷水合物合成路线 （共 107 条）
反应条件
hydrogenchloride; methanol
参考文献
Blicke; Godt
Journal of the American Chemical Society, 1954 , vol. 76, p. 2798
反应条件
in methanol
1 h; Heating;
参考文献
Orlov, V. D.; Papiashvili, I. Z.; Grigorov, P. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , vol. 19, # 5 p. 544 - 549
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 5 p. 671 - 676
参考文献
Pfleiderer; Blank
Angewandte Chemie, 1968 , vol. 80, p. 534
参考文献
Shimada, Junichi; Suzuki, Fumio; Nonaka, Hiromi; Karasawa, Akira; Mizumoto, Hideaki; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 466 - 469
参考文献
Kokel, B.; Viehe, H. G.; Declercq, J. P.; Germain, G.; Van Meerssche, M.
Tetrahedron Letters, 1980 , vol. 21, p. 3799 - 3800
反应条件
1: acetic acid
2: iodine / 1,2-dimethoxy-ethane / 50 °C
View Scheme
参考文献
Orlov, V. D.; Kolos, N. N.; Tueni, M.; Yur'eva, E. Yu.; Ivkov, S. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1992 , vol. 28, # 7 p. 788 - 794
Khimiya Geterotsiklicheskikh Soedinenii, 1992 , # 7 p. 947 - 954
反应条件
1: 92 percent / ethanol
2: 71 percent / 85 percent m-CPBA / acetonitrile / Ambient temperature
View Scheme
参考文献
De Araujo, Aline D.; Bacher, Edmond; Joachim Demnitz; Santos, Douglas A.
Heterocycles, 1999 , vol. 51, # 1 p. 29 - 36
反应条件
N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in water; acetonitrile
T=30 - 35°C; 2 h;
参考文献
Bandyopadhyay, Prabal; Agrawal, Sumit K.; Sathe, Manisha; Sharma, Pratibha; Kaushik
Tetrahedron, 2012 , vol. 68, # 20 p. 3822 - 3827
反应条件
1: 81 percent / ethanol
2: 90 percent / 85 percent m-CPBA / acetonitrile / Ambient temperature
View Scheme
参考文献
De Araujo, Aline D.; Bacher, Edmond; Joachim Demnitz; Santos, Douglas A.
Heterocycles, 1999 , vol. 51, # 1 p. 29 - 36
参考文献
Hager et al.
Journal of the American Pharmaceutical Association (1912-1977), 1954 , vol. 43, p. 152,154
Full Text Show Details
Krantz
Patent: US2840559 , 1954 ;
