2-乙酰氨基-2-[(2-甲基苯基)甲基]丙二酸二乙酯合成路线 （共 5 条）
参考文献
Herr et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 4229,4230
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; (Z,Z)-1,5-cyclooctadiene; [PdCp(η3-C3H5)] in tetrahydrofuran
T=80°C;
参考文献
Kuwano, Ryoichi; Kondo, Yutaka
Organic Letters, 2004 , vol. 6, # 20 p. 3545 - 3547
反应条件
sodium hydride; toluene
参考文献
Herr et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 4229,4230
反应条件
1: diethyl 2-acetylaminomalonate With sodium ethanolate in ethanol
0.5 h; Heating;
2: 2-methylbenzyl halide in ethanol
Heating;
参考文献
Varnavas, Antonio; Lassiani, Lucia; Valenta, Valentina; Mennuni, Laura; Makovec, Francesco; Hadjipavlou-Litina, Dimitra
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 6 p. 563 - 581
反应条件
(i) aq. NaOH, (ii) aq. HCl; Multistep reaction;
参考文献
Andrako,J. et al.
Journal of Pharmaceutical Sciences, 1961 , vol. 50, p. 337 - 340
