2-碘-5-甲氧基苯甲酸合成路线 （共 17 条）
反应条件
[bis(acetoxy)iodo]benzene; iodine; palladium diacetate; tetra-(n-butyl)ammonium iodide in 1,2-dichloro-ethane T=60°C; 12 h;
参考文献
Mei, Tian-Sheng; Giri, Ramesh; Maugel, Nathan; Yu, Jin-Quan
Angewandte Chemie - International Edition, 2008 , vol. 47, # 28 p. 5215 - 5219
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; 2: With potassium iodide in water T=0 - 70°C;
参考文献
Wu, Liang; Aliev, Abil E.; Caddick, Stephen; Fitzmaurice, Richard J.; Tocher, Derek A.; King, Frank D.
Chemical Communications, 2010 , vol. 46, # 2 p. 318 - 320
反应条件
[bis(acetoxy)iodo]benzene; lithium iodide in 1,1,1,3,3,3-hexafluoroisopropanol T=20°C;
参考文献
Hamamoto, Hiromi; Hattori, Sho; Takemaru, Kaori; Miki, Yasuyoshi
Synlett, 2011 , # 11 p. 1563 - 1566
反应条件
sodium hydroxide in methanol 5 h; Heating;
参考文献
Moss, Robert A.; Chatterjee, Swati; Wilk, Boguslawa
Journal of Organic Chemistry, 1986 , vol. 51, # 22 p. 4303 - 4307
反应条件
sodium hydroxide; water in methanol 4 h; Reflux;
参考文献
Uyanik, Muhammet; Akakura, Matsujiro; Ishihara, Kazuaki
Journal of the American Chemical Society, 2009 , vol. 131, p. 251 - 262
反应条件
hydrogenchloride pH=1;
参考文献
Nguyen, Thi-Huu; Chau, Nguyet Trang Thanh; Castanet, Anne-Sophie; Nguyen, Kim Phi Phung; Mortier, Jacques
Organic Letters, 2005 , vol. 7, # 12 p. 2445 - 2448
反应条件
1: s-BuLi; TMEDA; iodine / tetrahydrofuran / 0.5 h / -30 °C 2: 0.139 g / aq. HCl / 20 °C / pH 1 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 9 p. 3419 - 3429
反应条件
1: 67 percent / NaOEt / ethanol / 1.) 25 deg C, 4 d, 2.) reflux, 10 h 2: 71 percent / 1 M aq. NaOH / methanol / 5 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 51, # 22 p. 4303 - 4307
反应条件
1.1: sodium nitrite; hydrogenchloride / 0.5 h / 0 °C 1.2: 0.83 h / 0 - 90 °C 2.1: potassium carbonate / acetone / 5 h / |Reflux 3.1: sodium hydroxide / water; methanol / 2 h / |Reflux View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 17 p. 7360 - 7377
反应条件
1: potassium carbonate / acetone / 5 h / |Reflux 2: sodium hydroxide / water; methanol / 2 h / |Reflux View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 17 p. 7360 - 7377
