3-(3-噻吩)-丙烯酰氯合成路线 (共 2 条)
反应条件
thionyl chloride; N,N-dimethyl-formamide in chloroform
Heating; Yield given;
参考文献
New, James S.; Christopher, William L.; Yevich, Joseph P.; Butler, Rhett; Schlemmer, R. Francis; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1147 - 1156
反应条件
1: pyridine; piperidine / 13 h / 100 °C
2: thionyl chloride / chloroform; N,N-dimethyl-formamide / 3 h / |Reflux
View Scheme
参考文献
Li, Lingjun; Degardin, Melissa; Lavergne, Thomas; Malyshev, Denis A.; Dhami, Kirandeep; Ordoukhanian, Phillip; Romesberg, Floyd E.
Journal of the American Chemical Society, 2014 , vol. 136, # 3 p. 826 - 829