反应条件
1: 86 percent / HCl (gas) / CHCl3 / 1.) 1 h, 2.) -20 deg C, 10 min, 3.) room temperature, 1 h 2: 1.) n-butyllithium / 1.) THF, -78 deg C, hexane, 1 h, 2.) overnight, room temperature, 3.) ether 3: 58 percent / CuO, CuCl2 / acetone; H2O / 3.5 h / Heating 4: toluene / 18 h / 80 °C 5: 1.) lithium di-isopropylamide / 1.) -78 deg C, 25 min, THF, 2.) overnight, room temperature View Scheme
参考文献
Ramage, Robert; Griffiths, Gareth J.; Sweeney, John N. A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 7 p. 1547 - 1553
