4-(3-苯基-1,2,4-恶二唑-5-基)苯胺合成路线 （共 3 条）
反应条件
Na2S*9H2O in 1,4-dioxane; water
T=80°C; 0.75 h; Inert atmosphere;
参考文献
Conole, Daniel; Beck, Thorsten M.; Jay-Smith, Morgan; Tingle, Malcolm D.; Eason, Charles T.; Brimble, Margaret A.; Rennison, David
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2220 - 2235
反应条件
1: pyridine / 0.5 h / |Reflux; |Inert atmosphere
2: Na2S*9H2O / 1,4-dioxane; water / 0.75 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Conole, Daniel; Beck, Thorsten M.; Jay-Smith, Morgan; Tingle, Malcolm D.; Eason, Charles T.; Brimble, Margaret A.; Rennison, David
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2220 - 2235
反应条件
1: hydroxylamine hydrochloride; sodium hydroxide / water; ethanol / 36 h / |Inert atmosphere; |Reflux
2: pyridine / 0.5 h / |Reflux; |Inert atmosphere
3: Na2S*9H2O / 1,4-dioxane; water / 0.75 h / 80 °C / |Inert atmosphere
View Scheme
参考文献
Conole, Daniel; Beck, Thorsten M.; Jay-Smith, Morgan; Tingle, Malcolm D.; Eason, Charles T.; Brimble, Margaret A.; Rennison, David
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2220 - 2235
