2-氨基-6-(羟基甲基)-5,6,7,8-四氢-1H-喹唑啉-4-酮合成路线 (共 4 条)
反应条件
sodium tetrahydroborate; aluminium trichloride; diethylene glycol dimethyl ether
参考文献
Koehler et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 5779,5782
反应条件
lithium triethylborohydride in tetrahydrofuran
2 h;
参考文献
Nair; Dhawan; Ghazala; Kalman; Ferone; Gaumont; Kisliuk
Journal of Medicinal Chemistry, 1987 , vol. 30, # 7 p. 1256 - 1261
反应条件
1: methanol; sodium methylate
2: toluene-4-sulfonic acid-hydrate
3: NaBH4; AlCl3; O,O'-dimethyl-diethylene glycol
View Scheme
参考文献
Koehler et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 5779,5782
反应条件
1: toluene-4-sulfonic acid-hydrate
2: NaBH4; AlCl3; O,O'-dimethyl-diethylene glycol
View Scheme
参考文献
Koehler et al.
Journal of the American Chemical Society, 1958 , vol. 80, p. 5779,5782