吡啶-2.6-二羧酸二甲酯合成路线 （共 63 条）
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 68, # 1 p. 257 - 259
反应条件
4 A molecular sieve; sodium methylate Product distribution;
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 957 - 962
反应条件
Fe-complexe of pyridine-2,6-di-monothiocarboxylic acid in tetrahydrofuran 1 h; Ambient temperaturevar. reaction time and amounts of reaction partners, var. content of peroxides; Product distribution;
参考文献
Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, , vol. 39, # 1 p. 90 - 94
反应条件
4A molecular sives; potassium methanolate Product distribution;
参考文献
Journal of Heterocyclic Chemistry, , vol. 20, p. 957 - 962
反应条件
1-methyl-piperazine; sodium bis(2-methoxyethoxy)aluminium dihydride in toluene T=25°C; 3 h;
参考文献
Hagiya, Kazutake; Mitsui, Sunao; Taguchi, Hiroaki
Synthesis, 2003 , # 6 p. 823 - 828
反应条件
1: LiAlH4 / methanol 2: 45 percent / HBr View Scheme
参考文献
He, Zhicong; Chaimungkalanont, P. Jinny; Craig, Donald C.; Colbran, Stephen B.
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 2000 , # 9 p. 1419 - 1430
反应条件
sodium tetrahydroborate in methanol; dichloromethane T=0 - 20°C;
参考文献
GLOBAL BLOOD THERAPEUTICS, INC.; CYTOKINETICS, INC.; THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; METCALF, Brian; CHUANG, Chihyuan; WARRINGTON, Jeffrey; PAULVANNAN, Kumar; JACOBSON, Matthew P.; HUA, Lan; MORGAN, Bradley
Patent: WO2013/102145 A1, 2013 ;
Location in patent: Paragraph 0333 ;
反应条件
sodium tetrahydroborate in methanol Cooling with ice;
参考文献
Price, Eric W.; Cawthray, Jacqueline F.; Bailey, Gwendolyn A.; Ferreira, Cara L.; Boros, Eszter; Adam, Michael J.; Orvig, Chris
Journal of the American Chemical Society, 2012 , vol. 134, # 20 p. 8670 - 8683
反应条件
1: 41 percent / FeSO4*7H20; H2O2; H2SO4 / H2O / 15 - 30 °C 2: 81 percent / triethylamine / CH2Cl2 / 1.5 h / 0 - 20 °C View Scheme
参考文献
Tang, Rui-ren; Zhao, Qiang; Yan, Zi-er; Luo, Yi-ming
Synthetic Communications, 2006 , vol. 36, # 14 p. 2027 - 2034
反应条件
ammonium hydroxide T=40°C; 1 h;
参考文献
Helvetica Chimica Acta, , vol. 96, # 9 p. 1658 - 1669
