2-氯-4-(4-三氟甲基苯基)吡啶合成路线 (共 2 条)
反应条件
trichlorophosphate
T=100°C; 3 h;
参考文献
Merck Sharp and Dohme Limited
Patent: WO2004/46133 A1, 2004 ;
Location in patent: Page 33-34 ;
WO 2004/046133 A1
反应条件
copper(l) iodide; cesium fluoride in N,N-dimethyl-formamide
T=120°C; Hiyama Coupling; 12 h; Inert atmosphere;
参考文献
Gurung, Santosh K.; Thapa, Surendra; Vangala, Adarsh S.; Giri, Ramesh
Organic Letters, 2013 , vol. 15, # 20 p. 5378 - 5381