2,2’-二硫二苯甲酸二甲酯合成路线 （共 34 条）
参考文献
List; Stein
Chemische Berichte, 1898 , vol. 31, p. 1668
反应条件
1: 1,1-dioxo-3H-1,2-benzodithiol-3-one; 2-hydroxyethanethiol With water in acetonitrile
thiolation; 0.166667 h;
2: diazomethane in diethyl ether
T=24°C; Methylation; 0.0833333 h; Further byproducts given;
参考文献
Breydo, Leonid; Gates, Kent S.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 9 p. 885 - 889
反应条件
1: methyl 2-mercapto-benzoate With sodium in methanol
2: benzoyloxymethyl p-toluenethiosulfonate in acetone
T=20°C; 1 h;
参考文献
Kabir, S. M. Humayun; Langler, Richard F.
Australian Journal of Chemistry, 2005 , vol. 58, # 5 p. 362 - 367
反应条件
sodium methylate in methanol
15 h; Heating;
参考文献
Nandi, Bidisha; Kundu, Nitya G.
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 14 p. 1649 - 1655
反应条件
1: methyl 2-mercapto-benzoate With sodium in methanol
2: 2-Benzoyloxymethyldisulfanyl-benzoic acid methyl ester in acetone
T=20°C; 1 h;
参考文献
Kabir, S. M. Humayun; Langler, Richard F.
Australian Journal of Chemistry, 2005 , vol. 58, # 5 p. 362 - 367
反应条件
1: methyl 2-mercapto-benzoate With sodium in methanol
2: C17H16O4S3 in acetone
T=20°C; 1 h;
参考文献
Kabir, S. M. Humayun; Langler, Richard F.
Australian Journal of Chemistry, 2005 , vol. 58, # 5 p. 362 - 367
反应条件
in tetrahydrofuran
T=20°C; 0.5 h;
参考文献
Shimizu, Masao; Fukazawa, Hidenori; Inoue, Jun'ichi; Abe, Yoshimoto; Konakahara, Takeo
Heterocycles, 2007 , vol. 71, # 1 p. 61 - 73
反应条件
in toluene
72 h; Heating;
参考文献
Davis, Franklin A.; Jenkins, Linda A.; Billmers, Robert L.
Journal of Organic Chemistry, 1986 , vol. 51, # 7 p. 1033 - 1040
反应条件
in toluene
T=100°C; Cyclization; 5 h;
参考文献
Shimizu, Masao; Kikumoto, Hisashi; Konakahara, Takeo; Gama, Yasuo; Shibuya, Isao
Heterocycles, 1999 , vol. 51, # 12 p. 3005 - 3012
反应条件
Et3N-4HF in ethylene glycol dimethyl ether
T=20°C; Electrochemical reaction;
参考文献
Yin, Bin; Inagi, Shinsuke; Fuchigami, Toshio
Synlett, 2011 , # 9 p. 1313 - 1317
