3-羟基-3-甲基壬酸乙酯合成路线 （共 13 条）
反应条件
1: KOH / methanol 2: Cu / quinoline View Scheme
参考文献
Vilkas,M.; Abraham,N.A.
Bulletin de la Societe Chimique de France, 1960 , p. 1196 - 1201
反应条件
1: alcoholic KOH View Scheme
参考文献
Fieser et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 3209
反应条件
1: alcoholic KOH 2: HCl / bei langsamer Destillation unter Entfernung des entstehenden Wassers View Scheme
参考文献
Fieser et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 3209
反应条件
1: P2O5 / benzene / 6 h / Heating 2: H2 / PtO2 / methanol 3: aq. NaOH View Scheme
参考文献
Kletzke,P.G.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1363 - 1366
反应条件
zinc(II) chloride in tetrahydrofuran; toluene
1.) 20 deg C, 90 min, 2.) 20 deg C, 3 h;
参考文献
Majkosza, Mieczyslaw; Nieczypor, Piotr; Grela, Karol
Tetrahedron, 1998 , vol. 54, # 36 p. 10827 - 10836
反应条件
AcrH(+)ClO4(-) in dichloromethane
T=-78°C; 4 h;
参考文献
Otera, Junzo; Wakahara, Yoshiyuki; Kamei, Hidenobu; Sato, Tsuneo; Nozaki, Hitosi; Fukuzumi, Shunichi
Tetrahedron Letters, 1991 , vol. 32, # 21 p. 2405 - 2408
反应条件
1: ethyl acetate With lithium hexamethyldisilazane in tetrahydrofuran
T=-70°C;
2: n-hexyl methyl ketone in tetrahydrofuran
Reformatsky reaction;
参考文献
Suri, Suresh C.; Marcischak, Jacob C.
Synthetic Communications, 2005 , vol. 35, # 3 p. 379 - 387
反应条件
magnesium; mercury dichloride in diethyl ether
参考文献
Kletzke,P.G.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1363 - 1366
反应条件
diethyl ether; magnesium
参考文献
Bouveault; Blanc
Bulletin de la Societe Chimique de France, 1904 , vol. <3> 31, p. 1209
Chem. Zentralbl., 1905 , vol. 76, # II p. 1701
反应条件
1: P2O5 / benzene / 6 h / Heating
2: H2 / PtO2 / methanol
3: LiAlH4 / diethyl ether
View Scheme
参考文献
Kletzke,P.G.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1363 - 1366
