N-(6-甲氧基喹啉-8-基)丁烷-1,4-二胺合成路线 （共 9 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430
反应条件
ethanol; hydrazine hydrate
参考文献
Cope et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 554,560
Full Text Show Details
Beer
Zhurnal Obshchei Khimii, 1939 , vol. 9, p. 2158,2161
Chem. Zentralbl., 1940 , vol. 111, # I p. 3112
Full Text Show Details
Robinson; Tomlinson
Journal of the Chemical Society, 1934 , p. 1524,1528
反应条件
1: 100 percent / H2 / Raney-Ni / 1 h / 20 °C / 2585.74 Torr
2: Et3N / 6 h / 150 °C
3: H2NNH2*H2O / ethanol / 3 h / Heating
View Scheme
参考文献
Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430
反应条件
1: 70 percent / Fe, AcOH / 0.2 h / 118 °C
2: 17 percent / As2O5, H3PO4 / 1 h / 100 °C
3: 100 percent / H2 / Raney-Ni / 1 h / 20 °C / 2585.74 Torr
4: Et3N / 6 h / 150 °C
5: H2NNH2*H2O / ethanol / 3 h / Heating
View Scheme
参考文献
Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430
反应条件
1: 17 percent / As2O5, H3PO4 / 1 h / 100 °C
2: 100 percent / H2 / Raney-Ni / 1 h / 20 °C / 2585.74 Torr
3: Et3N / 6 h / 150 °C
4: H2NNH2*H2O / ethanol / 3 h / Heating
View Scheme
参考文献
Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430
反应条件
1: Et3N / 6 h / 150 °C
2: H2NNH2*H2O / ethanol / 3 h / Heating
View Scheme
参考文献
Armer, Richard E.; Barlow, Jacqueline S.; Chopra, Narinder; Dutton, Christopher J.; Greenway, David H.J.; Greenwood, Sean D.W.; Lad, Nita; Shaw, Jonothan; Thompson, Adrian P.; Thong, Kam-Wah; Tommasini, Ivan
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 16 p. 2425 - 2430
反应条件
ethanol; platinum
P=102971 Torr; Hydrogenation;
参考文献
Drake et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 455,457
反应条件
ethanol; platinum
P=102971 Torr; Hydrogenation;
参考文献
Drake et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 455,457
参考文献
Drake; Garman
Journal of the American Chemical Society, 1949 , vol. 71, p. 2425
