5-乙氧基-2-苯基-1,3-恶唑-4-羧酸合成路线 （共 18 条）
反应条件
1: 86 percent / oxalyl chloride, DMF / CH2Cl2; diethyl ether / 2 h / Ambient temperature
2: 78 percent / aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
3: 84 percent / toluene / 1.5 h / Heating
View Scheme
参考文献
Turchi, Ignatius J.; Maryanoff, Cynthia A.
Synthesis, 1983 , # 10 p. 837 - 839
反应条件
1: 86 percent / oxalyl chloride, DMF / CH2Cl2; diethyl ether / 2 h / Ambient temperature
2: aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
3: toluene / 1.5 h / Heating
View Scheme
参考文献
Turchi, Ignatius J.; Maryanoff, Cynthia A.
Synthesis, 1983 , # 10 p. 837 - 839
反应条件
1: 86 percent / oxalyl chloride, DMF / CH2Cl2; diethyl ether / 2 h / Ambient temperature
2: 78 percent / aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Turchi, Ignatius J.; Maryanoff, Cynthia A.
Synthesis, 1983 , # 10 p. 837 - 839
反应条件
1: 86 percent / oxalyl chloride, DMF / CH2Cl2; diethyl ether / 2 h / Ambient temperature
2: aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Turchi, Ignatius J.; Maryanoff, Cynthia A.
Synthesis, 1983 , # 10 p. 837 - 839
反应条件
1: 86 percent / oxalyl chloride, DMF / CH2Cl2; diethyl ether / 2 h / Ambient temperature
2: 72 percent / aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Turchi, Ignatius J.; Maryanoff, Cynthia A.
Synthesis, 1983 , # 10 p. 837 - 839
反应条件
1: 86 percent / oxalyl chloride, DMF / CH2Cl2; diethyl ether / 2 h / Ambient temperature
2: 88 percent / aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Turchi, Ignatius J.; Maryanoff, Cynthia A.
Synthesis, 1983 , # 10 p. 837 - 839
反应条件
1: 86 percent / oxalyl chloride, DMF / CH2Cl2; diethyl ether / 2 h / Ambient temperature
2: 89 percent / aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Turchi, Ignatius J.; Maryanoff, Cynthia A.
Synthesis, 1983 , # 10 p. 837 - 839
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in diethyl ether; dichloromethane
2 h; Ambient temperature;
参考文献
Turchi, Ignatius J.; Maryanoff, Cynthia A.
Synthesis, 1983 , # 10 p. 837 - 839
