2-(4-氯苯基)喹啉-4-甲酸合成路线 （共 3 条）
反应条件
potassium hydroxide in ethanol
T=50 - 60°C; 14 h;
参考文献
Nicolaie, E; Guengoer, T; Goyard, J; Cure, G; Fouquet, A; et al.
European Journal of Medicinal Chemistry, 1992 , vol. 27, # 9 p. 977 - 984
反应条件
[Yb(PFO)3] in water
Doebner reaction; 3 h; Reflux;
参考文献
Wang, Li-Min; Hu, Liang; Chen, Hong-Juan; Sui, Yuan-Yuan; Shen, Wei
Journal of Fluorine Chemistry, 2009 , vol. 130, # 4 p. 406 - 409
反应条件
1: SOCl2
2: diethyl ether
3: tin (II)-chloride; aq.-ethanolic hydrochloric acid
View Scheme
参考文献
Lutz et al.
Journal of the American Chemical Society, 1946 , vol. 68, p. 1810
