4-氯-6,7-二氢-5H-环戊二烯并[b]吡啶合成路线 (共 4 条)
反应条件
1: With lithium chloride in acetonitrile T=20°C; 0.166667 h; 2: With trichlorophosphate in water; acetonitrile T=20 - 80°C; 3: With sodium carbonate in water; acetonitrile T=20°C; 0.666667 h;
参考文献
WO2009/19274 A1, ;
Page/Page column 32 ;
反应条件
T=650°C; 0.26 h; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 103, # 6 p. 1525 - 1533
反应条件
T=400°C; 0.35 h; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 103, # 6 p. 1525 - 1533
反应条件
dihydrogen peroxide; methyltrioxorhenium (VII) in dichloromethane T=20°C; 25 h;
参考文献
JANSSEN PHARMACEUTICA NV
Patent: WO2009/19274 A1, 2009 ;
Location in patent: Page/Page column 33 ;